Metabolic

5-Amino-1MQ

$49
COA Available
A selective small molecule inhibitor of nicotinamide N-methyltransferase—increasing cellular NAD+ availability through enzymatic blockade of the methylation pathway.
FormOral Capsule
Quantity50mg
Purity≥98%
SequenceChemical structure: 5-amino-1-methylquinolinium (small molecule, not a peptide)
CAS Number42464-96-0
Molecular Weight159.2 g/mol
Molecular FormulaC10H11N2+
Third-Party Tested
Next Day Ship
Free $150+
Quantity:
1
Request COA

Product Overview

Affordable 5-Amino-1-methylquinolinium for metabolic research. NNMT inhibitor shown to affect cellular metabolism and energy expenditure in preclinical models.

Value Proposition:

Research Applications

NNMT inhibition studies, cellular metabolism research, NAD+ salvage pathway investigations. Published rodent studies employ various dosing regimens based on research objectives.

What's Included

50mg 5-Amino-1MQ powder, Certificate of Analysis confirming purity, reconstitution guidelines. Store at -20°C. Reconstitute in appropriate solvent for your research application.

Reconstitution

Use our peptide calculator to determine bacteriostatic water volume and target concentration.

Storage & Handling

Store at room temperature (15-30°C) in sealed container protected from moisture. This small molecule exhibits excellent stability. For research use, dissolve in appropriate vehicle according to experimental protocol.

Frequently Asked Questions

How should I reconstitute this product?

Reconstitute with bacteriostatic water (supplied with order). Add water slowly down the side of the vial, allow to dissolve naturally without shaking.

What purity testing is performed?

All products undergo dual verification: manufacturer HPLC testing (≥98% purity) plus independent third-party lab verification. Certificates of Analysis are available for every batch—request via email at support@prcpeptides.com.

How should I store this product?

Lyophilized (powder): Store at -20°C in original sealed vial. Reconstituted: Store at 2-8°C (refrigerated) and use within 30 days. Do not freeze reconstituted product. Keep away from direct light.

Do you provide Certificates of Analysis?

Yes. Every product has an available COA from both the manufacturer and our independent third-party testing lab. Request your batch-specific COA by emailing support@prcpeptides.com with your order number.

References

  1. Kannt A, et al. "Association of nicotinamide-N-methyltransferase mRNA expression in human adipose tissue and the plasma concentration of its product, 1-methylnicotinamide, with insulin resistance." Diabetologia. 2015;58(4):799-808. PMID: 25596853
  2. Kraus D, et al. "Nicotinamide N-methyltransferase knockdown protects against diet-induced obesity." Nature. 2014;508(7495):258-262. PMID: 24717514
  3. Brachs S, et al. "Inhibition of NNMT reduces adipocyte lipid content and adipose tissue inflammation." Diabetologia. 2019;62(3):541-551. PMID: 30556429
  4. Kraus D, et al. "NNMT inhibition as a therapeutic approach to obesity." Curr Opin Clin Nutr Metab Care. 2018;21(4):258-263. PMID: 29727306
  5. Hong S, et al. "Nicotinamide N-methyltransferase regulates hepatic nutrient metabolism through Sirt1 protein stabilization." Nat Med. 2015;21(8):887-894. PMID: 26168295
FOR RESEARCH PURPOSES ONLY. This product is intended exclusively for in vitro laboratory research and is not for human consumption, diagnostic use, or therapeutic applications.
5-Amino-1MQ
$49